Chronologie du Yémen (1045-1131/1635-1719)

Chronologie Chemie 1800–1970

John Addenbrooke M.D. (1680-1719).

WHEN A PUBLIC benefactor is neither a well-known local or national figure nor the subject of contemporary writings, an eponymous benefaction may be his only memorial. Such is the case of John Addenbrooke, who founded the hospital at Cambridge which bears his name. He spent a third of his short life of thirty-nine years in residence at Catharine Hall (now St. Catharine's College) of which he bec...

Dmd059055 1719..1726

The purpose of this study was to demonstrate experimentally that alterations of in vivo transporter function at the blood-brain barrier (BBB) in disease and during pharmacotherapy can be reconstructed from in vitro data based on our established pharmacoproteomic concept of reconstructing in vivo function by integrating intrinsic transport activity per transporter molecule and absolute protein e...

yoISSN 1045-6333 HARVARD

A prominent theoretical controversy in the compensating differentials literature concerns unobservable individual productivity. Competing models yield opposite predictions depending on whether the unobservable productivity is safety-related skill or productivity generally. Using five panel waves and several new measures of worker fatality risks, first-difference estimates imply that omitting in...

Dmd063362 1045..1055

Hepatic OATPs 1B1, 1B3 and 2B1, as well as P-gp, play important roles in regulating liver uptake and biliary excretion of drugs. The intrinsic ethnic variability in OATP1B1-mediated hepatic uptake of statins has been proposed to underlie the ethnic variability in plasma exposures of statins between Caucasians and Asians. Using a targeted quantitative proteomic approach, we determined hepatic pr...